Lovastatin Has Significant Activity against Zygomycetes and Interacts Synergistically with Voriconazole
نویسندگان
چکیده
منابع مشابه
Lovastatin has significant activity against zygomycetes and interacts synergistically with voriconazole.
Zygomycetes are emerging opportunistic molds resistant to most conventional antifungals. We evaluated the in vitro activity of lovastatin (LOV), a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, against seven clinical isolates of Zygomycetes by using standard microdilution methods in three different media, disk diffusion testing, and viability dye staining. To further study the in vi...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2006
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.50.1.96-103.2006